Invitrogen™ TRPC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA572874

Catalog No. PIPA572874

Description

TRPC3 Polyclonal Antibody for Western Blot, IHC (P), ELISA

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

Specifications

• Antigen: TRPC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Trpc3
• Gene Alias: hTrp3; hTrp-3; ion channel protein; mTrp3; Mwk; receptor-activated cation channel TRP3; SCA41; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; transient receptor protein 3; Trcp3; Trp3; TRP-3; TRPC3; TrpC3c; trp-related protein 3; Trrp3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22065, 60395, 7222
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q13507, Q9JMI9, Q9QZC1
• Gene Symbols: Trpc3
• Immunogen: TRPC3 antibody for a 19 amino acid peptide from near the carboxy terminus of human TRPC3. The immunogen is within amino acids 710 - 760 of TRPC3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG