TRPC4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 213491AP
DescriptionTRPC4 is a member of the canonical subfamily of transient receptor potential cation channels. TRPC4 forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in TRPC4 may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRPC4. The classical or canonical transient receptor potential (TRPC) channels are the subfamily most closely related to the founding member of the TRP family, the Drosophila TRP channel. TRPC channels have seven TRPC genes that encode the channel protein (TRPC1-7). Diseases associated with TRPC4 include Photosensitive Epilepsy.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O35119, Q9QUQ5, Q9UBN4|
|hTrp 4, HTRP4, Trp related protein 4, TRP4, TRPC4|
|22066, 7223, 84494|
|Immunohistochemistry (Paraffin), Western Blot|
|TRPC4 Fusion Protein Ag15698|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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