TRPC4AP Mouse anti-Human, Clone: 2C10B1, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 661381IG150UL

Catalog No. 50-173-6574

Description

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Specifications

• Antigen: TRPC4AP
• Classification: Monoclonal
• Concentration: 0.96 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8TEL6
• Gene Symbols: TRPC4AP
• Immunogen: TRPC4AP Fusion Protein Ag18772
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG3

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 2C10B1
• Conjugate: Unconjugated
• Gene: TRPC4AP
• Gene Alias: C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 26133
• Content And Storage: -20°C
• Form: Liquid