Invitrogen™ TRPC7 Monoclonal Antibody (N64A/36), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545473

Catalog No. PIMA545473

Description

1 μg/mL of MA5-45473 was sufficient for detection of TrpC7 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 100kDa.

TRPC7 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC7 is probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC7 is also activated by diacylglycerol (DAG). Further, TRPC7 may also be activated by intracellular calcium store depletion.

Specifications

• Antigen: TRPC7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: Q9HCX4, Q9WVC5
• Gene Symbols: TRPC7
• Immunogen: Synthetic peptide amino acids 845-862 of human TRPC7.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Microarray
• Clone: N64A/36
• Conjugate: APC
• Gene: TRPC7
• Gene Alias: capacitative calcium channel TRPC7; hTRP7; likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7; mTRP7; putative capacitative calcium channel; short transient receptor potential channel 7; transient receptor potential cation channel subfamily C member 7; transient receptor potential cation channel, subfamily C, member 7; transient receptor protein 7; TRP7; TRP-7; TRP7 protein; TRPC7; Trrp8
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 26946, 282822, 57113
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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