Invitrogen™ TRPM5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588498

Catalog No. PIPA588498

Description

Immunogen sequence: RVFKKEAEHK REHLERDLPD PLDQKVVTWE TVQKENFLSK MEKRRRDSEG EVLRKTAHRV DFIAKYLGGL REQEKRIKCL ESQINYCSVL VSSVADVLAQ GGGPRSSQHC GEGSQLVAAD HRGGLDGWEQ PGAGQPPSDT; Positive Samples: U-87MG, Mouse liver, Mouse brain; Cellular Location: Cell membrane, Multi-pass membrane protein.

This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Caions. It is activated by lower concentrations of intracellular Ca, and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15. 5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

Specifications

• Antigen: TRPM5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: trpm5
• Gene Alias: 9430099A16Rik; Long transient receptor potential channel 5; long transient receptor potential-related channel 5; LTRPC5; LTrpC-5; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; MTR1; si:dkey-56p7.1; transient receptor potential cation channel subfamily M member 5; transient receptor potential cation channel, subfamily M, member 5; transient receptor potential melastatin 5; TRPM5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29850, 56843
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.84 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9JJH7, Q9NZQ8
• Gene Symbols: trpm5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1026-1165 of human TRPM5 (NP_0553701).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG