Invitrogen™ TRPM7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587618

Catalog No. PIPA587618

Description

Immunogen sequence: NSWYKVILSI LVPPAILLLE YKTKAEMSHI PQSQDAHQMT MDDSENNFQN ITEEIPMEVF KEVRILDSNE GKNEMEIQMK SKKLPITRKF YAFYHAPIVK; Positive Samples: Mouse skeletal muscle; Cellular Location: Membrane, Multi-pass membrane protein.

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.

Specifications

• Antigen: TRPM7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Trpm7
• Gene Alias: 2310022G15Rik; 4833414K03Rik; 5033407O22Rik; ALSPDC; CHAK; CHAK1; Channel kinase 1; Channel-kinase 1; FLJ20117; long transient receptor potential channel 7; long transient receptor potential channel 7 {ECO:0000250; Ltpr7; LTRPC ion channel family member 7; LTRPC7; LTrpC-7; LTrpC7 {ECO:0000250; PubMed:11161216}; RGD:620053}; tr; transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7 {ECO:0000312; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential M7; transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-phospholipase C-interacting kinase {ECO:0000303; transient receptor potential-related protein, ChaK; TRMP7; TRP PLIK; Trpm7; trpm7 {ECO:0000312; TRPPLIK; Trp-plik; TRP-PLIK {ECO:0000303; UniProtKB:Q96QT4}
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58800
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.96 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q923J1
• Gene Symbols: Trpm7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 756-855 of human TRPM7 (NP_0601423).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG