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Invitrogen™ TRPM8 Polyclonal Antibody
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Catalog No. PIPA534286
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50 μg
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PIPA534286 50 μg
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Catalog No. PIPA534286 Supplier Invitrogen™ Supplier No. PA534286
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Description

Rabbit Polyclonal Antibody

TRPM8 Polyclonal Antibody for IHC (P)

TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. TRPM8 is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. TRPM8 is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. TRPM8 has an expression pattern within normal human tissues that is mostly restricted to prostate epithelial cells. TRPM8 mRNA expression is at moderate levels in normal prostate tissue and appears to be elevated in prostate cancer. Notably, TRPM8 mRNA was also expressed in a number of nonprostatic primary tumors of breast, colon, lung, and skin origin, whereas transcripts encoding TRPM8 were hardly detected or not detected in the corresponding normal human tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPM8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene TRPM8
Gene Accession No. Q7Z2W7, Q8R455, Q8R4D5
Gene Alias CMR1; Cold menthol receptor 1; cold/menthol receptor 1; long transient receptor potential channel 6; LTRPC6; LTrpC-6; MGC2849; short form of the TRPM8 cationic channel; transient receptor melastatin 8 variant 1; transient receptor melastatin 8 variant 2; transient receptor potential cation channel subfamily M member 8; transient receptor potential cation channel, subfamily M, member 8; transient receptor potential p8; transient receptor potential subfamily M member 8; transient receptor potential-p8; TRP ion channel TRPM8; Trpm8; Trpp8; trp-p8
Gene Symbols TRPM8
Host Species Rabbit
Immunogen Synthetic 15 amino acid peptide from internal region of human TRPM8.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100057419, 100337634, 100351107, 100754189, 171382, 171384, 424025, 486170, 79054
Target Species Human, Mouse, Rat, Canine, Rabbit, Hamster, Horse, Chicken, Guinea Pig, Bat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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