TRPM8 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-8269	150 μL

Catalog No. 50-172-8269 Supplier Proteintech Group Inc Supplier No. 128131AP150UL

Description

Rabbit Polyclonal Antibody

TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. TRPM8 is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. TRPM8 is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. TRPM8 has an expression pattern within normal human tissues that is mostly restricted to prostate epithelial cells. TRPM8 mRNA expression is at moderate levels in normal prostate tissue and appears to be elevated in prostate cancer. Notably, TRPM8 mRNA was also expressed in a number of nonprostatic primary tumors of breast, colon, lung, and skin origin, whereas transcripts encoding TRPM8 were hardly detected or not detected in the corresponding normal human tissues.

Specifications

• Antigen: TRPM8
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.15 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: TRPM8
• Gene Accession No.: Q7Z2W7
• Gene Alias: LTrpC 6, LTRPC6, Trp p8, TRPM8, TRPP8
• Gene Symbols: TRPM8
• Host Species: Rabbit
• Immunogen: TRPM8 Fusion Protein Ag3483
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 79054
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG