Invitrogen™ TRPML3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553725

Catalog No. PIPA553725

Description

Immunogen sequence: YENKGTKQSA MAICQHFYKR GNIYPGNDTF DIDPEIETEC FFVEPDEPFH IGTPAENKLN LTLDFHRLLT VELQFKLKAI NLQTVRHQEL PDCYDFTLT Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 87%.

Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.

Specifications

• Antigen: TRPML3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MCOLN3
• Gene Alias: 6720490O21Rik; FLJ11006; FLJ36629; MCLN3; Mcoln3; Mcoln3 mucolipin 3; MGC124245; MGC124246; MGC71509; mucolipin 3; mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3; TRP-ML3; Va; varitint-waddler
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55283
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TDD5
• Gene Symbols: MCOLN3
• Immunogen: Recombinant protein corresponding to Human Mucolipin 3. Recombinant protein control fragment (Product #RP-91207).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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