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Invitrogen™ TRPML3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA553725
Description
Immunogen sequence: YENKGTKQSA MAICQHFYKR GNIYPGNDTF DIDPEIETEC FFVEPDEPFH IGTPAENKLN LTLDFHRLLT VELQFKLKAI NLQTVRHQEL PDCYDFTLT Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 87%.
Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.
Specifications
TRPML3 | |
Polyclonal | |
Unconjugated | |
MCOLN3 | |
6720490O21Rik; FLJ11006; FLJ36629; MCLN3; Mcoln3; Mcoln3 mucolipin 3; MGC124245; MGC124246; MGC71509; mucolipin 3; mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3; TRP-ML3; Va; varitint-waddler | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
55283 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q8TDD5 | |
MCOLN3 | |
Recombinant protein corresponding to Human Mucolipin 3. Recombinant protein control fragment (Product #RP-91207). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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