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Invitrogen™ TRPML3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553725

Catalog No. PIPA553725


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Description

Description

Immunogen sequence: YENKGTKQSA MAICQHFYKR GNIYPGNDTF DIDPEIETEC FFVEPDEPFH IGTPAENKLN LTLDFHRLLT VELQFKLKAI NLQTVRHQEL PDCYDFTLT Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 87%.

Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRPML3
Polyclonal
Unconjugated
MCOLN3
6720490O21Rik; FLJ11006; FLJ36629; MCLN3; Mcoln3; Mcoln3 mucolipin 3; MGC124245; MGC124246; MGC71509; mucolipin 3; mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3; TRP-ML3; Va; varitint-waddler
Rabbit
Antigen affinity chromatography
RUO
55283
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q8TDD5
MCOLN3
Recombinant protein corresponding to Human Mucolipin 3. Recombinant protein control fragment (Product #RP-91207).
100 μL
Primary
Human
Antibody
IgG
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