Invitrogen™ TRPML3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109339

Catalog No. PIPA5109339

Description

Positive Control: 293 cell, F9.

Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.

Specifications

• Antigen: TRPML3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MCOLN3
• Gene Alias: 6720490O21Rik; FLJ11006; FLJ36629; MCLN3; Mcoln3; Mcoln3 mucolipin 3; MGC124245; MGC124246; MGC71509; mucolipin 3; mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3; TRP-ML3; Va; varitint-waddler
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171166, 55283
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8R4F0, Q8TDD5
• Gene Symbols: MCOLN3
• Immunogen: Synthetic peptide within Human TRPML3 aa 504-553.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG