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Invitrogen™ TRPV2 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA518989
Description
This antibody is predicted to react with mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
VLR-1 is a calcium-permeable, non-selective cation channel with an outward rectification, that seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. VRL-1 does not respond to capsaicin, acid, or moderate heat, but instead is activated by high temperatures, with a threshold of approximately 52 degrees C. Within sensory ganglia, VRL-1 is most prominently expressed by a subset of medium- to large-diameter neurons, making it a candidate receptor for transducing high-threshold heat responses in this class of cells. VRL-1 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. VRL-1 is one of the six members of the vanilloid-like TRP-channel family which is now known as TRPV family.
Specifications
TRPV2 | |
Polyclonal | |
Unconjugated | |
Trpv2 | |
GRC; growth factor regulated channel; growth factor-regulated calcium channel; Osm-9-like TRP channel 2; OTRPC2; RP23-234K24.7; Sac2b; Stretch-activated channel 2B; transient receptor potential cation channel subfamily V member 2; transient receptor potential cation channel, subfamily V, member 2; Trpv2; Vanilloid receptor-like protein 1; VRL; Vrl1; VRL-1 | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
22368 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunocytochemistry | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
Q9WTR1 | |
Trpv2 | |
Synthetic peptide sequence (SEEDHLPLQVLQSH) corresponding to the C-terminus amino acids of TRPV2 (aa 743-756). | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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