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Invitrogen™ TRPV2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518989

Catalog No. PIPA518989


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Description

Description

This antibody is predicted to react with mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

VLR-1 is a calcium-permeable, non-selective cation channel with an outward rectification, that seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. VRL-1 does not respond to capsaicin, acid, or moderate heat, but instead is activated by high temperatures, with a threshold of approximately 52 degrees C. Within sensory ganglia, VRL-1 is most prominently expressed by a subset of medium- to large-diameter neurons, making it a candidate receptor for transducing high-threshold heat responses in this class of cells. VRL-1 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. VRL-1 is one of the six members of the vanilloid-like TRP-channel family which is now known as TRPV family.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRPV2
Polyclonal
Unconjugated
Trpv2
GRC; growth factor regulated channel; growth factor-regulated calcium channel; Osm-9-like TRP channel 2; OTRPC2; RP23-234K24.7; Sac2b; Stretch-activated channel 2B; transient receptor potential cation channel subfamily V member 2; transient receptor potential cation channel, subfamily V, member 2; Trpv2; Vanilloid receptor-like protein 1; VRL; Vrl1; VRL-1
Goat
Ammonium sulfate precipitation
RUO
22368
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunocytochemistry
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q9WTR1
Trpv2
Synthetic peptide sequence (SEEDHLPLQVLQSH) corresponding to the C-terminus amino acids of TRPV2 (aa 743-756).
100 μg
Primary
Mouse
Antibody
IgG
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