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Invitrogen™ TRPV3 Monoclonal Antibody (N15/39), APC
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Catalog No. PIMA545454
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100 μg
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PIMA545454 100 μg
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Catalog No. PIMA545454 Supplier Invitrogen™ Supplier No. MA545454
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45454 was sufficient for detection of TrpV3 in 10 μg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody Detects approximately 70kDa.

TRPV3 belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPV3
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Microarray
Classification Monoclonal
Clone N15/39
Concentration 1 mg/mL
Conjugate APC
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
Gene TRPV3
Gene Accession No. Q8K424, Q8NET8
Gene Alias 1110036I10Rik; AI644701; FNEPPK2; heat sensitive channel TRPV3; MGC124324; MGC124325; Nh; non-hair; OLMS; Transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRP ion channel TRPV3; TrpV3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; VRL 3; VRL3; VRL-3
Gene Symbols TRPV3
Host Species Mouse
Immunogen Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 162514, 246788, 497948
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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