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Invitrogen™ TRPV4 Polyclonal Antibody
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Catalog No. PIPA534291
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50 μg
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PIPA534291 50 μg
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Catalog No. PIPA534291 Supplier Invitrogen™ Supplier No. PA534291
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%) Marmoset (94%) Panda, Dog (89%) Hamster, Bovine, Pig (83%).

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPV4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.91 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Trpv4
Gene Accession No. Q9HBA0
Gene Alias 0610033B08Rik; BCYM3; CMT2C; HMSN2C; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 4; OSM9-like transient receptor potential channel 4; osm-9-like TRP channel 4; osmosensitive transient receptor potential channel 4; Otrpc4; SMAL; SPSMA; SSQTL1; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel, subfamily 5, member 4; transient receptor potential cation channel, subfamily V, member 4; transient receptor potential protein 12; Trp12; Trpv4; trpv4 channel; Vanilloi; vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; vanilloid receptor-related osmotically activated channel; vanilloid receptor-related osmotically activated channel (Vroac); vanilloid receptor-related osmotically activated channel protein; vanilloid receptor-related osmotically-activated channel; Vrl2; VRL-2; VROAC; VR-OAC; wu:fp52e02
Gene Symbols Trpv4
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide from N-terminus of human TRPV4.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 59341
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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