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Invitrogen™ TrxR1 Polyclonal Antibody
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Catalog No. PIPA581936
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100 μL
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PIPA581936 100 μL
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Catalog No. PIPA581936 Supplier Invitrogen™ Supplier No. PA581936
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SCEDGRALEG TLSELAAETD LPVVFVKQRK IGGHGPTLKA YQEGRLQKLL KMNGPEDLPK SYDYDLIIIG GGSGGLAAAK EAAQYGKKVM VLDFVTPTPL GTRWGLGGTC VNVGCIPKKL MHQAALLGQA LQDSRNYG Highest antigen sequence indentity to the following orthologs: Mouse - 59%, Rat - 59%.

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TrxR1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TXNRD1
Gene Accession No. Q16881
Gene Alias gene associated with retinoic and IFN-induced mortality 12 protein; gene associated with retinoic and interferon-induced mortality 12 protein; GRIM12; GRIM-12; KDRF; KM-102-derived reductase-like factor; MGC9145; NADPH-dependent thioredoxin reductase; oxidoreductase; selenoprotein oxidoreductase; testis tissue sperm-binding protein Li 46a; thioredoxin reductase 1; thioredoxin reductase 1, cytoplasmic; thioredoxin reductase GRIM-12; thioredoxin reductase TR1; TR; TR alpha; TR1; Trxr1; TXNR; Txnrd1
Gene Symbols TXNRD1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TXNRD1. Recombinant protein control fragment (Product #RP-94768).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7296
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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