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Invitrogen™ TrxR1 Polyclonal Antibody
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Catalog No. PIPA5116094
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PIPA5116094 100 μL
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Catalog No. PIPA5116094 Supplier Invitrogen™ Supplier No. PA5116094
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TXNRD1.

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TrxR1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene TXNRD1
Gene Accession No. O89049, Q16881, Q9JMH6
Gene Alias gene associated with retinoic and IFN-induced mortality 12 protein; gene associated with retinoic and interferon-induced mortality 12 protein; GRIM12; GRIM-12; KDRF; KM-102-derived reductase-like factor; MGC9145; NADPH-dependent thioredoxin reductase; oxidoreductase; selenoprotein oxidoreductase; testis tissue sperm-binding protein Li 46a; thioredoxin reductase 1; thioredoxin reductase 1, cytoplasmic; thioredoxin reductase GRIM-12; thioredoxin reductase TR1; TR; TR alpha; TR1; Trxr1; TXNR; Txnrd1
Gene Symbols TXNRD1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TXNRD1(Accession Q16881), corresponding to amino acid residues Y302-D323.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50493, 58819, 7296
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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