Invitrogen™ Trypsin 2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121523

Catalog No. PIPA5121523

Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Trypsin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRSS2
• Gene Alias: anionic trypsin; anionic trypsin II; Anionic trypsin-2; anionic trypsinogen; EC 3.4.21; EC 3.4.21.4; MGC111183; MGC120174; MGC120175; pancreatic anionic trypsinogen; pancreatic trypsin 2; pancreatic trypsin II; pretrypsinogen II; protease serine 2 preproprotein; protease, serine 2; protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS2; Ptryss2; Serine protease 2; Ta; Tesp4; Try2; TRY8; TRYP; TRYP2; TRYP8; trypsin 2; trypsin II; trypsin Trypsin II; Trypsin-2; trypsinogen 2; trypsinogen 20; trypsinogen anionic precursor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100525899, 5645
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P07478
• Gene Symbols: PRSS2
• Immunogen: Ile24-Asp241 (Accession P07478), with N-terminal His Tag.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig
• Product Type: Antibody
• Isotype: IgG