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Invitrogen™ Trypsin 2 Recombinant Rabbit Monoclonal Antibody (3D9O7)
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Catalog No. PIMA537902
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PIMA537902 100 μL
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Catalog No. PIMA537902 Supplier Invitrogen™ Supplier No. MA537902
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse pancreas, Rat pancreas Immunogen sequence: MNLLLILTFV AAAVAAPFDD DDKIVGGYIC EENSVPYQVS LNSGYHFCGG SLISEQWVVS AGHCYKSRIQ VRLGEHNIEV LEGNEQFINA AKIIRHPKYN.

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Trypsin 2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 3D9O7
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene PRSS2
Gene Accession No. P00763, P07146, P07478
Gene Alias anionic trypsin; anionic trypsin II; Anionic trypsin-2; anionic trypsinogen; EC 3.4.21; EC 3.4.21.4; MGC111183; MGC120174; MGC120175; pancreatic anionic trypsinogen; pancreatic trypsin 2; pancreatic trypsin II; pretrypsinogen II; protease serine 2 preproprotein; protease, serine 2; protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS2; Ptryss2; Serine protease 2; Ta; Tesp4; Try2; TRY8; TRYP; TRYP2; TRYP8; trypsin 2; trypsin II; trypsin Trypsin II; Trypsin-2; trypsinogen 2; trypsinogen 20; trypsinogen anionic precursor
Gene Symbols PRSS2
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22072, 25052, 5645
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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