Invitrogen™ Trypsin Monoclonal Antibody (TRYP11-236.7), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA546011

Catalog No. PIMA546011

Description

MA1-10617 detects Trypsin from human samples. MA1-10617 has been successfully used in ELISA applications. The MA1-10617 immunogen is purified human pancreatic Trypsin.

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.

Specifications

• Antigen: Trypsin
• Classification: Monoclonal
• Concentration: 0.6 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P07477
• Gene Symbols: PRSS1
• Immunogen: Purified human pancreatic Trypsin.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: TRYP11-236.7
• Conjugate: Unconjugated
• Gene: PRSS1
• Gene Alias: Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; anionic trypsin-1; Anionic trypsinogen; beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pretrypsinogen I; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS1; PRSS2; PTRYI; RATPTRYI; Serine protease 1; Serine protease 2; TCR V beta 4.1; TRP1; Try1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP1; TRYP2; TRYP8; trypsin 1; Trypsin I; Trypsin II; trypsin-1; Trypsin-2; trypsinogen; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen A
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5644
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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