Invitrogen™ Trypsin Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547544

Catalog No. PIPA547544

Description

In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant human (rh) Trypsin 2 and rhTrypsin 3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.

Specifications

• Antigen: Trypsin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRSS1
• Gene Alias: Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; anionic trypsin-1; Anionic trypsinogen; beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pretrypsinogen I; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS1; PRSS2; PTRYI; RATPTRYI; Serine protease 1; Serine protease 2; TCR V beta 4.1; TRP1; Try1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP1; TRYP2; TRYP8; trypsin 1; Trypsin I; Trypsin II; trypsin-1; Trypsin-2; trypsinogen; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen A
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5644
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P07477
• Gene Symbols: PRSS1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Trypsin 1/PRSS1 Ala16-Ser247.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG