Trypsin Polyclonal Antibody, Biotin, Rockland™

Catalog No.	Quantity
50-199-0988	25 μL
50-199-0987	100 μg

Catalog No. 50-199-0988 Supplier Rockland Immunochemicals Supplier No. 200406139S

Description

Rabbit Polyclonal Antibody

Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Trypsin Antibody is an IgG fraction purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Biotin, anti-Rabbit Serum as well as purified and partially purified Trypsin [Bovine Pancreas]. Cross reactivity against Trypsin from other sources may occur but has not been specifically determined.

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.

Specifications

• Antigen: Trypsin
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Biotin
• Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
• Gene: PRSS2
• Gene Alias: Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; Anionic trypsin II; Anionic trypsin-1; Anionic trypsin-2; Anionic trypsinogen; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pancreatic trypsin 2; pancreatic trypsin II; Pretrypsinogen I; Pretrypsinogen II; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); Prss1; PRSS2; PTRYI; Ptryss2; RATPTRYI; Serine protease 1; Serine protease 2; Ta; TCR V beta 4.1; Tesp4; TRP1; TRY1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP; TRYP1; TRYP2; TRYP8; trypsin 1; trypsin 2; Trypsin I; Trypsin II; Trypsin-1; Trypsin-2; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen 20; trypsinogen A
• Gene Symbols: PRSS1, PRSS2
• Host Species: Rabbit
• Immunogen: Anti-Trypsin Antibody was produced by repeated immunizations with bovine pancreatic trypsin protein purified.
• Quantity: 25 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 282603, 615026
• Target Species: Bovine
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Lyophilized