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Trypsin Polyclonal Antibody, Invitrogen™

Catalog No. PIPA588532
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PIPA588532 100 μL
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Catalog No. PIPA588532 Supplier Thermo Scientific Supplier No. PA588532

Description

Rabbit Polyclonal Antibody

Immunogen sequence: IVGGYNCEEN SVPYQVSLNS GYHFCGGSLI NEQWVVSAGH CYKSRIQVRL GEHNIEVLEG NEQFINAAKI IRHPQYDRKT LNNDIMLIKL SSRAVINARV STISLPTAPP ATGTKCLISG WGNTASSGAD YPDELQCLDA PVLSQAKCEA SYPGKITSNM FCVGFLEGGK DSCQGDSGGP VVCNGQLQGV VSWGDGCAQK NKPGVYTKVY NYVKWIKNTI AANS; Positive Samples: HT-29, Mouse spleen, Mouse kidney; Cellular Location: extracellular space

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Trypsin
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 4.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PRSS1
Gene Accession No. P07477
Gene Symbols Prss1
Host Species Rabbit
Immunogen Recombit fusion protein containing a sequence corresponding to amino acids 24-247 of human PRSS1
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114228, 5644
Target Species Human, Mouse
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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