TSC22D1 Monoclonal Antibody (OTI1A5), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-5603	100 μL
50-253-9950	30 μL

Catalog No. 50-167-5603 Supplier OriGene Supplier No. TA505048

Description

Mouse Monoclonal Antibody

TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.

Specifications

• Antigen: TSC22D1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1A5
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TSC22D1
• Gene Accession No.: Q15714
• Gene Alias: Ptg-2, TGFB1I4, TSC22
• Gene Symbols: TSC22D1
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TSC22D1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8848
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b