TSC22D1 Mouse anti-Human, Clone: OTI1A5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF505048

Catalog No. 50-166-3344

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.

Specifications

• Antigen: TSC22D1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TSC22D1
• Gene Alias: Ptg-2, TGFB1I4, TSC22
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8848
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1A5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q15714
• Gene Symbols: TSC22D1
• Immunogen: Full length human recombit protein of human TSC22D1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b