Invitrogen™ TSC22D1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA586488

Catalog No. PIPA586488

Description

Purity is > 95% by SDS-PAGE.

TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.

Specifications

• Antigen: TSC22D1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tsc22d1
• Gene Alias: AA589566; AW105905; Cerebral protein 2; Egr5; hucep-2; Kiaa1994; Ptg-2; regulatory protein Tsc22; Regulatory protein TSC-22; RP11-269C23.2; short tandem repeat locus PEZ20 variant 19; Tgfb1i4; TGFbeta-stimulated clone 22; Tgfb-stimulated clone 22 homolog; Tilz1b; transcriptional regulator TSC-22; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta stimulated clone 22; transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TS22A; Tsc; Tsc22; TSC-22; TSC22 domain family member 1; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22D1; Tsc22-related inducible leucine zipper 1b
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21807, 498545, 8848
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P62500, P62501, Q15714
• Gene Symbols: Tsc22d1
• Immunogen: Synthetic peptide, corresponding to amino acids 41-93 of Human TSC22.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG