Invitrogen™ TSC22D1 Recombinant Rabbit Monoclonal Antibody (040)

Catalog No.	Quantity
PIMA529619	100 μL

Catalog No. PIMA529619 Supplier Invitrogen™ Supplier No. MA529619

Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human TSC22D1.

TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.

Specifications

• Antigen: TSC22D1
• Applications: Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 040
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: Tsc22d1
• Gene Accession No.: Q15714
• Gene Alias: AA589566; AW105905; Cerebral protein 2; Egr5; hucep-2; Kiaa1994; Ptg-2; regulatory protein Tsc22; Regulatory protein TSC-22; RP11-269C23.2; short tandem repeat locus PEZ20 variant 19; Tgfb1i4; TGFbeta-stimulated clone 22; Tgfb-stimulated clone 22 homolog; Tilz1b; transcriptional regulator TSC-22; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta stimulated clone 22; transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TS22A; Tsc; Tsc22; TSC-22; TSC22 domain family member 1; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22D1; Tsc22-related inducible leucine zipper 1b
• Gene Symbols: Tsc22d1
• Host Species: Rabbit
• Immunogen: Recombinant Human TSC22D1 Protein (Met1-Ala144).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8848
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG