TSC22D3 Monoclonal Antibody (OTI1E11), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-5855	100 μL
50-253-9746	30 μL

Catalog No. 50-167-5855 Supplier OriGene Supplier No. TA505368

Description

Mouse Monoclonal Antibody

The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.

Specifications

• Antigen: TSC22D3
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1E11
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TSC22D3
• Gene Accession No.: Q99576
• Gene Alias: DIP, DSIPI, GILZ, TSC-22R
• Gene Symbols: TSC22D3
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TSC22D3 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1831
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1