Invitrogen™ TSC22D4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540333

Catalog No. PIPA540333

Description

Peptide sequence: SGGKKKSSFQ ITSVTTDYEG PGSPGASDPP TPQPPTGPPP RLPNGEPSPD Sequence homology: Dog: 90%; Guinea Pig: 93%; Human: 100%; Rat: 77%.

TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1. Binds DNA and acts as a transcriptional repressor (PubMed:10488076). Involved in the regulation of systematic glucose homeostasis and insulin sensitivity, via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity). Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490). May play a role in neurite elongation and survival (By similarity).

Specifications

• Antigen: TSC22D4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tsc22d4
• Gene Alias: 0610009M14Rik; 1700023B23Rik; AI415410; LOW QUALITY PROTEIN: TSC22 domain family protein 4; THG1; THG-1; Thg1pit; Thg-1pit; Tilz2; TSC22 domain family 4; TSC22 domain family member 4; TSC22 domain family protein 4; TSC22 domain family, member 4; Tsc22d4; tsc-22-like protein THG-1; TSC22-related inducible leucine zipper 2; TSC22-related-inducible leucine zipper protein 2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 81628
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9Y3Q8
• Gene Symbols: Tsc22d4
• Immunogen: Synthetic peptide directed towards the N-terminal of human TSC22D4 (aa 2-51).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG