Invitrogen™ TSC22D4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568854

Catalog No. PIPA568854

Description

This target displays homology in the following species: Cow: 90%; Guinea Pig: 90%; Human: 90%; Mouse: 100%; Rabbit: 90%; Rat: 100%.

TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1. Binds DNA and acts as a transcriptional repressor (PubMed:10488076). Involved in the regulation of systematic glucose homeostasis and insulin sensitivity, via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity). Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490). May play a role in neurite elongation and survival (By similarity).

Specifications

• Antigen: TSC22D4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tsc22d4
• Gene Alias: 0610009M14Rik; 1700023B23Rik; AI415410; LOW QUALITY PROTEIN: TSC22 domain family protein 4; THG1; THG-1; Thg1pit; Thg-1pit; Tilz2; TSC22 domain family 4; TSC22 domain family member 4; TSC22 domain family protein 4; TSC22 domain family, member 4; Tsc22d4; tsc-22-like protein THG-1; TSC22-related inducible leucine zipper 2; TSC22-related-inducible leucine zipper protein 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 78829
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9EQN3
• Gene Symbols: Tsc22d4
• Immunogen: Synthetic peptide directed towards the middle region of mouse TSC22D4 (aa 241-290).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov