TSEN15 Monoclonal Antibody (OTI3F5), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4663	100 μL

Catalog No. 50-168-4663 Supplier OriGene Supplier No. TA812720

Description

Mouse Monoclonal Antibody

Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5′ and 3′ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2′,3′ cyclic phosphate and 5′-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3′-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3′-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

Specifications

• Antigen: TSEN15
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI3F5
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TSEN15
• Gene Accession No.: Q8WW01
• Gene Alias: C1orf19, PCH2F, sen15
• Gene Symbols: TSEN15
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TSEN15 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 116461, 289083
• Target Species: Human, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1