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Invitrogen™ TSEN15 Polyclonal Antibody
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Catalog No. PIPA556087
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PIPA556087 100 μL
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Catalog No. PIPA556087 Supplier Invitrogen™ Supplier No. PA556087
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EERGDSEPTP GCSGLGPDGV RGFGDGGGAP SWAPEDAWMG THPKYLEMME LDIGDATHVY VAFLVYLDLM ESK Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.

Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSEN15
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tsen15
Gene Accession No. Q8WW01
Gene Alias 5730449L18Rik; AL023077; C16H1ORF19; C1orf19; HsSEN15; PCH2F; RGD1308584; sen15; SEN15 homolog; tRNA splicing endonuclease 15 homolog; tRNA splicing endonuclease 15 homolog (S. cerevisiae); tRNA splicing endonuclease subunit 15; tRNA-intron endonuclease Sen15; tRNA-splicing endonuclease subunit Sen15; Tsen15; TSEN15 tRNA splicing endonuclease subunit; Unknown (protein for MGC:127982)
Gene Symbols Tsen15
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TSEN15. Recombinant protein control fragment (Product #RP-94557).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116461
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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