Invitrogen™ TSG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578540

Catalog No. PIPA578540

Description

Positive Control: A549 Predicted Reactivity: Rat (97%), Xenopus laevis (88%), Chicken (98%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TWSG1 may be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.

Specifications

• Antigen: TSG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Twsg1
• Gene Alias: 1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403e; PSEC0250; Tsg; Twg; twisted gastrulation BMP signaling modulator 1; twisted gastrulation homolog 1; twisted gastrulation homolog 1 (Drosophila); twisted gastrulation protein homolog 1; Twsg1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57045, 65960
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9EP52, Q9GZX9
• Gene Symbols: Twsg1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human TWSG1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov