Invitrogen™ TSH Receptor Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142806

Catalog No. PIPA5142806

Description

Additional Information: This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

TSH Receptor gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: TSH Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TSHR
• Gene Alias: AI481368; CHNG1; hTSHR-I; hypothroid; hyt; LGR3; MGC141920; pet; seven transmembrane helix receptor; thyroid stimulating hormone receptor; thyroid stimulating hormone receptor, isoform 2; thyroid-stimulating hormone receptor; thyroid-stimulating hormone receptor variant; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSHR; TSH-R; TSHR; seven transmembrane domain G protein-coupled receptor; TSHRA
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 7253
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P16473
• Gene Symbols: TSHR
• Immunogen: Peptide with sequence C-SKVTHIEIRNTRNLT (aa 101-115).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG