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Invitrogen™ TSHZ3 Polyclonal Antibody
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Catalog No. PIPA534344
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100 μg
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Catalog No. Quantity
PIPA534344 100 μg
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Catalog No. PIPA534344 Supplier Invitrogen™ Supplier No. PA534344
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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse brain tissue lysate. PA5-34344 can be used with blocking peptide PEP-1387.

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSHZ3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Tshz3
Gene Accession No. D3ZKB9, Q63HK5, Q8CGV9
Gene Alias A630038G13Rik; Kiaa1474; mKIAA1474; teashirt 3; teashirt homolog 3; teashirt zinc finger family member 3; teashirt zinc finger homeobox 3; teashirt3; Tsh3; Tshz3; Zfp537; zinc finger protein 537; ZNF537
Gene Symbols Tshz3
Host Species Rabbit
Immunogen An 18 amino acid synthetic peptide near the amino terminus of human TSHZ3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 243931, 308523, 57616
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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