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Invitrogen™ TSHZ3 Polyclonal Antibody
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Catalog No. PIPA552616
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PIPA552616 100 μL
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Catalog No. PIPA552616 Supplier Invitrogen™ Supplier No. PA552616
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TNFHAMEELV KKVTEKVAKV EEKMKEPDGK LSPPKRATPS PCSSEVGEPI KMEASSDGGF RSQENSPSPP RDGCKDGSPL AEPVENGKEL VKPLASSLSG STAIITDHP Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 88%.

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSHZ3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tshz3
Gene Accession No. Q63HK5
Gene Alias A630038G13Rik; Kiaa1474; mKIAA1474; teashirt 3; teashirt homolog 3; teashirt zinc finger family member 3; teashirt zinc finger homeobox 3; teashirt3; Tsh3; Tshz3; Zfp537; zinc finger protein 537; ZNF537
Gene Symbols Tshz3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TSHZ3. Recombinant protein control fragment (Product #RP-89336).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57616
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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