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Invitrogen™ TSKU Polyclonal Antibody
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Catalog No. PIPA598217
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100 μL
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PIPA598217 100 μL
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Catalog No. PIPA598217 Supplier Invitrogen™ Supplier No. PA598217
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Description

Rabbit Polyclonal Antibody

TSKU Polyclonal Antibody for Western Blot, ELISA

The TSKU gene encodes Tsukushi, a member of the small leucine-rich proteoglycan (SLRP) family, playing crucial roles in cellular signaling, growth, and development. Tsukushi is characterized by its involvement in various biological processes, including immune regulation, tissue remodeling, and metabolic homeostasis. It is a hepatokine released in response to conditions like nonalcoholic fatty liver disease (NAFLD), influencing metabolic traits and contributing to conditions such as dyslipidemia and cardiovascular diseases. Tsukushi impacts energy expenditure by modulating brown fat thermogenesis, thereby affecting metabolic homeostasis and obesity-related metabolic traits. As an extracellular matrix component, Tsukushi participates in signaling pathways that regulate cell proliferation, migration, and differentiation, impacting organ development and pathophysiological processes. Its role in metabolic and inflammatory diseases presents it as a potential biomarker and therapeutic target in conditions characterized by altered metabolic and inflammatory states. Ongoing research further elucidates Tsukushi's mechanisms and interactions, contributing to our understanding of its multifunctional roles in health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSKU
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene TSKU
Gene Accession No. Q8WUA8
Gene Alias 9530051K01Rik; E2ig4; E2-induced gene 4 protein; Early insulin-induced hepatic gene protein; Eiih; hepatic protein EIIH; leucine rich repeat containing 54; leucine-rich repeat-containing protein 54; LRRC54; Tsk; Tsku; Tsukushi; tsukushi homolog; tsukushi small leucine rich proteoglycan homolog; tsukushi, small leucine rich proteoglycan; tsukushin; UNQ850/PRO1788
Gene Symbols TSKU
Host Species Rabbit
Immunogen Recombinant Human Tsukushin protein (77-353AA).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25987
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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