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Invitrogen™ TSLP Polyclonal Antibody
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Catalog No. PIPA520319
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100 μg
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Catalog No. Quantity
PIPA520319 100 μg
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Catalog No. PIPA520319 Supplier Invitrogen™ Supplier No. PA520319
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Description

Rabbit Polyclonal Antibody

Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is Jurkat cell lysate. PA5-20319 can be used with blocking peptide PEP-0439.

TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSLP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TSLP
Gene Accession No. Q969D9
Gene Alias Thymic stroma-derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Gene Symbols TSLP
Host Species Rabbit
Immunogen A 17 amino acid synthetic peptide from near the carboxy terminus of human TSLP.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 85480
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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