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Invitrogen™ TSN Monoclonal Antibody (OTI1B5)

Description
TSN Monoclonal Antibody for Western Blot, IHC (P)
Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
Specifications
Specifications
| Antigen | TSN |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI1B5 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | Tsn |
| Gene Accession No. | Q15631 |
| Gene Alias | 2610034C24Rik; AU040286; BCLF-1; C3PO; Component 3 of promoter of RISC; RCHF1; recombination hotspot associated factor; recombination hotspot-binding protein; REHF-1; TBRBP; TB-RBP; testis brain-RNA binding protein; testis/brain RNA-binding protein; testis/brain-RNA-binding protein; translin; TRSLN; Tsn |
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