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Invitrogen™ TSN Polyclonal Antibody
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Catalog No. PIPA5116869
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100 μL
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PIPA5116869 100 μL
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Catalog No. PIPA5116869 Supplier Invitrogen™ Supplier No. PA5116869
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Description

Rabbit Polyclonal Antibody

Positive Samples: K-562, HeLa, Mouse spleen, Mouse brain, Rat thymus, Rat spleen Immunogen sequence: GFQDIPKRCL KAREHFGTVK THLTSLKTKF PAEQYYRFHE HWRFVLQRLV FLAAFVVYLE TETLVTREAV TEILGIEPDR EKGFHLDVED YLSGVLILAS E.

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSN
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Tsn
Gene Accession No. Q15631, Q62348
Gene Alias 2610034C24Rik; AU040286; BCLF-1; C3PO; Component 3 of promoter of RISC; RCHF1; recombination hotspot associated factor; recombination hotspot-binding protein; REHF-1; TBRBP; TB-RBP; testis brain-RNA binding protein; testis/brain RNA-binding protein; testis/brain-RNA-binding protein; translin; TRSLN; Tsn
Gene Symbols Tsn
Host Species Rabbit
Immunogen Synthetic Peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22099, 60381, 7247
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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