Invitrogen™ TSN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116869

Catalog No. PIPA5116869

Description

Positive Samples: K-562, HeLa, Mouse spleen, Mouse brain, Rat thymus, Rat spleen Immunogen sequence: GFQDIPKRCL KAREHFGTVK THLTSLKTKF PAEQYYRFHE HWRFVLQRLV FLAAFVVYLE TETLVTREAV TEILGIEPDR EKGFHLDVED YLSGVLILAS E.

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

Specifications

• Antigen: TSN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tsn
• Gene Alias: 2610034C24Rik; AU040286; BCLF-1; C3PO; Component 3 of promoter of RISC; RCHF1; recombination hotspot associated factor; recombination hotspot-binding protein; REHF-1; TBRBP; TB-RBP; testis brain-RNA binding protein; testis/brain RNA-binding protein; testis/brain-RNA-binding protein; translin; TRSLN; Tsn
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22099, 60381, 7247
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.72 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q15631, Q62348
• Gene Symbols: Tsn
• Immunogen: Synthetic Peptide.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG