Invitrogen™ TSN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563747

Catalog No. PIPA563747

Description

Immunogen sequence: MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG F Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

Specifications

• Antigen: TSN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tsn
• Gene Alias: 2610034C24Rik; AU040286; BCLF-1; C3PO; Component 3 of promoter of RISC; RCHF1; recombination hotspot associated factor; recombination hotspot-binding protein; REHF-1; TBRBP; TB-RBP; testis brain-RNA binding protein; testis/brain RNA-binding protein; testis/brain-RNA-binding protein; translin; TRSLN; Tsn
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7247
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15631
• Gene Symbols: Tsn
• Immunogen: Recombinant protein corresponding to Human TSN. Recombinant protein control fragment (Product #RP-101621).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov