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Invitrogen™ TSSK6 Polyclonal Antibody
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Catalog No. PIPA575952
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PIPA575952 100 μL
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Catalog No. PIPA575952 Supplier Invitrogen™ Supplier No. PA575952
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSSK6
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene TSSK6
Gene Accession No. Q925K9, Q9BXA6
Gene Alias Cancer/testis antigen 72; CT72; FKSG82; RGD1559764; serine/threonine protein kinase SSTK; serine/threonine-protein kinase SSTK; Small serine/threonine kinase; SSTK; testis secretory sperm-binding protein Li 205a; testis specific serine kinase 6; testis-specific kinase 6; testis-specific serine kinase 6; testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK4; TSSK6; TSSK-6
Gene Symbols TSSK6
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 110-155 of Human TSSK6A.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290670, 83983, 83984
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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