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TSSK6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989300
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50-198-9300 100 μL
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Catalog No. 50-198-9300 Supplier Bioss Supplier No. BS9734R
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Description

Rabbit Polyclonal Antibody

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.

Specifications

Antigen TSSK6
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TSSK6
Gene Accession No. Q9BXA6
Gene Alias Cancer/testis antigen 72; CT72; FKSG82; RGD1559764; serine/threonine protein kinase SSTK; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; Sstk; testis secretory sperm-binding protein Li 205a; testis specific serine kinase 6; testis-specific kinase 6; testis-specific serine kinase 6; Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK4; TSSK6; TSSK-6
Gene Symbols TSSK6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TSSK6/CT72.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83983
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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