Invitrogen™ TTBK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520686

Catalog No. PIPA520686

Description

A suggested positive control is Jurkat cell lysate. PA5-20686 can be used with blocking peptide PEP-0802.

TTBK1 is a member of the casein kinase 1 superfamily, and it functions as a neuron-specific serine/threonine and tyrosine kinase. Its primary role is to regulate the phosphorylation of tau, a protein that stabilizes microtubule assemblies. It has been found that genetic variants in this gene are linked to Alzheimer's disease. Additionally, TTBK1 is associated with several other diseases, including Childhood-Onset Schizophrenia and Spinocerebellar Ataxia 11.

Specifications

• Antigen: TTBK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTBK1
• Gene Alias: AU017937; AW048023; BDTK; Brain-derived tau kinase; C330008L01Rik; KIAA1855; RP3-330M21.4; tau tubulin kinase 1; tau-tubulin kinase 1; Ttbk1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 106763, 84630
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q5TCY1, Q6PCN3
• Gene Symbols: TTBK1
• Immunogen: A 16 amino acid peptide near the carboxy terminus of human TTBK1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG