Invitrogen™ TTBK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556840

Catalog No. PIPA556840

Description

Immunogen sequence: RLVMEKRQGR LLLRLASGAS SSSSEEQRRA SETLSGTGSE EDTPASEPAA ALPRKSGRAA ATRSRIPRPI GLRMPMPVAA QQ Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.

TTBK1 is a member of the casein kinase 1 superfamily, and it functions as a neuron-specific serine/threonine and tyrosine kinase. Its primary role is to regulate the phosphorylation of tau, a protein that stabilizes microtubule assemblies. It has been found that genetic variants in this gene are linked to Alzheimer's disease. Additionally, TTBK1 is associated with several other diseases, including Childhood-Onset Schizophrenia and Spinocerebellar Ataxia 11.

Specifications

• Antigen: TTBK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTBK1
• Gene Alias: AU017937; AW048023; BDTK; Brain-derived tau kinase; C330008L01Rik; KIAA1855; RP3-330M21.4; tau tubulin kinase 1; tau-tubulin kinase 1; Ttbk1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84630
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5TCY1
• Gene Symbols: TTBK1
• Immunogen: Recombinant protein corresponding to Human TTBK1. Recombinant protein control fragment (Product #RP-94885).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG