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Invitrogen™ TTC21B Polyclonal Antibody
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Catalog No. PIPA5140036
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100 μL
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PIPA5140036 100 μL
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Catalog No. PIPA5140036 Supplier Invitrogen™ Supplier No. PA5140036
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: LQGRVKEALK WYKTAMTLDE TSVSALVGFI QCQLIEGQLQ DADQQLEFLN EIQQSIGKSA ELIYLHAVLA MKKNKRQEEV INLLNDVLDT HF Highest antigen sequence indentity to the following orthologs: Rat - 50%, Mouse - 77%.

The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTC21B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TTC21B
Gene Accession No. Q7Z4L5
Gene Alias 2410066K11Rik; aln; ATD4; IFT139; IFT139B; Intraflagellar transport 139 homolog; JBTS11; Kiaa1992; line 158; mKIAA1992; Nbla10696; NPHP12; putative protein product of Nbla10696; RGD1565122; SRTD4; tetratricopeptide repeat domain 21B; tetratricopeptide repeat protein 21B; Tetratricopeptide repeat-containing hedgehog modulator 1; Thm1; TPR repeat protein 21B; Ttc21b
Gene Symbols TTC21B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TTC21B. Recombinant protein control fragment (Product #RP-109336).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79809
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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