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Invitrogen™ TTC30A Polyclonal Antibody
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Catalog No. PIPA5113089
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100 μg
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PIPA5113089 100 μg
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Catalog No. PIPA5113089 Supplier Invitrogen™ Supplier No. PA5113089
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Rabbit Polyclonal Antibody

TTC30A Polyclonal Antibody for Western Blot, IHC (P), ELISA

The TTC30A gene encodes for the Tetratricopeptide Repeat Domain 30A, which is part of the intraflagellar transport (IFT) complex B, critical for ciliary function. TTC30A and its paralog TTC30B are involved in the stability and functioning of the IFT complex. These proteins play a redundant role in maintaining cilia integrity, necessary for proper cellular signaling and homeostasis. Disruption of TTC30A, through CRISPR/Cas9 gene editing, has shown to impair ciliogenesis, leading to developmental defects such as limb malformations and polycystic kidney disease due to altered tubulin acetylation and ciliary transport. This highlights the importance of TTC30A in cellular and developmental processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTC30A
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene TTC30A
Gene Accession No. Q86WT1
Gene Alias IFT70A; tetratricopeptide repeat domain 30A; tetratricopeptide repeat domain 30B; tetratricopeptide repeat protein 30A; TPR repeat protein 30A; TTC30A
Gene Symbols TTC30A
Host Species Rabbit
Immunogen Recombinant Human Tetratricopeptide repeat protein 30A protein (201-500AA).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 92104
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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