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Invitrogen™ TTC40 Polyclonal Antibody
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Catalog No. PIPA558571
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PIPA558571 100 μL
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Catalog No. PIPA558571 Supplier Invitrogen™ Supplier No. PA558571
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VKALQKMCLH ELTVPVLQLG VLISDSVVGS KGLSDLYHLR LAHACSELKL REAAARHEEA VGQVCVSELE QASCR Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 29%.

The TTC40 gene, which stands for Tetratricopeptide repeat domain 40, is a member of the TPR protein family characterized by highly conserved motifs that facilitate protein-protein interactions. This gene plays a significant role in various cellular processes, including signal transduction and protein assembly. TTC40 has been identified as a novel methylated gene in nasopharyngeal carcinoma, where its expression is significantly reduced in tumor tissues due to hypermethylation. This epigenetic alteration suggests a potential role of TTC40 in tumorigenesis, possibly acting as a tumor suppressor. The decreased expression of TTC40 in cancerous tissues highlights its importance in maintaining cellular homeostasis and integrity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTC40
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CFAP46
Gene Accession No. Q8IYW2
Gene Alias 9330101J02Rik; bA288G11.4; bA288G11.5; bB137A17.2; bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93; CFAP46; cilia and flagella associated protein 46; cilia- and flagella-associated protein 46; E030019B06Rik; Gm170; protein CFAP46; RGD1559985; similar to chromosome 10 open reading frame 92; tetratricopeptide repeat domain 40; tetratricopeptide repeat protein 40; TPR repeat-containing protein C10orf93; TTC40
Gene Symbols CFAP46
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TTC40. Recombinant protein control fragment (Product #RP-103677).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54777
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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