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Invitrogen™ TTC40 Polyclonal Antibody
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Catalog No. PIPA531570
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100 μL
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PIPA531570 100 μL
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Catalog No. PIPA531570 Supplier Invitrogen™ Supplier No. PA531570
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HCT116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The TTC40 gene, which stands for Tetratricopeptide repeat domain 40, is a member of the TPR protein family characterized by highly conserved motifs that facilitate protein-protein interactions. This gene plays a significant role in various cellular processes, including signal transduction and protein assembly. TTC40 has been identified as a novel methylated gene in nasopharyngeal carcinoma, where its expression is significantly reduced in tumor tissues due to hypermethylation. This epigenetic alteration suggests a potential role of TTC40 in tumorigenesis, possibly acting as a tumor suppressor. The decreased expression of TTC40 in cancerous tissues highlights its importance in maintaining cellular homeostasis and integrity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTC40
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CFAP46
Gene Accession No. Q8IYW2
Gene Alias 9330101J02Rik; bA288G11.4; bA288G11.5; bB137A17.2; bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93; CFAP46; cilia and flagella associated protein 46; cilia- and flagella-associated protein 46; E030019B06Rik; Gm170; protein CFAP46; RGD1559985; similar to chromosome 10 open reading frame 92; tetratricopeptide repeat domain 40; tetratricopeptide repeat protein 40; TPR repeat-containing protein C10orf93; TTC40
Gene Symbols CFAP46
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human C10orf93. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54777
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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