Invitrogen™ TTC5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560894

Catalog No. PIPA560894

Description

Immunogen sequence: GALTHCRNKV SLQNLSMVLR QLRTDTEDEH SHHVMDSVRQ AKLAVQMDVH DGRSWYILGN SYLSLYFSTG QNPKISQQAL SAYAQAEKVD RKASSNPDL Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.

Specifications

• Antigen: TTC5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTC5
• Gene Alias: Strap; stress-responsive activator of p300; tetratricopeptide repeat domain 5; tetratricopeptide repeat protein 5; TPR repeat protein 5; TTC5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91875
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N0Z6
• Gene Symbols: TTC5
• Immunogen: Recombinant protein corresponding to Human TTC5. Recombinant protein control fragment (Product #RP-100595).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG