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Invitrogen™ TTC5 Polyclonal Antibody
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Catalog No. PIPA589101
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100 μL
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PIPA589101 100 μL
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Catalog No. PIPA589101 Supplier Invitrogen™ Supplier No. PA589101
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MMADEEEEVK PILQKLQELV DQLYSFRDCY FETHSVEDAG RKQQDVQKEM EKTLQQMEEV VGSVQGKAQV LMLTGKALNV TPDYSPKAEE LLSKAVKLEP ELVEAWNQLG EVYWKKGDVA AAHTCFSGAL THCRNKVSLQ NLSMVLRQLR TDTEDEHSHH VMDSVRQAKL AVQMDVHDGR SWYILGNSYL SLYFSTGQNP KISQQALSAY AQAEKVDRKA SSNPDLHLNR ATLHKYEESY GEALEGFSRA AALDPAWPEP RQREQQLLEF LDRLTSLLES KGKVKTKKLQ SMLGSLRPAH; Positive Samples: A-431, MCF-7, Mouse spleen, Mouse testis, Mouse thymus, Rat brain; Cellular Location: Cytoplasm, Nucleus.

Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTC5
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TTC5
Gene Accession No. Q8N0Z6, Q99LG4
Gene Alias Strap; stress-responsive activator of p300; tetratricopeptide repeat domain 5; tetratricopeptide repeat protein 5; TPR repeat protein 5; TTC5
Gene Symbols TTC5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC5 (NP_6123852).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 219022, 91875
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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