Invitrogen™ Nkx2.1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575369

Catalog No. PIPA575369

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Nkx2.1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NKX2-1
• Gene Alias: AV026640; BCH; BHC; homeobox protein NK-2 homolog A; Homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2.1; Nkx-2.1; NKX2-1; NKX2A; NMTC1; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1 TTF-1 NK-2; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; tinman; TITF1; TTF1; TTF-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21869, 25628, 7080
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P23441, P43699, P50220
• Gene Symbols: NKX2-1
• Immunogen: Synthetic peptide corresponding to the N-terminal of Human TTF1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG